Carver Charitable Trust Leaders Visit New Biomechanics, Mechanobiology Laboratory

Troy Ross, executive administrator, and Lynne Sasmazer, program director, at the Roy J. Carver Charitable Trust visited the newly

finished Carver Biomechanics & Mechanobiology Laboratory May 21 at the Seamans Center for the Engineering Arts and Sciences.

The laboratory is a gift of the charitable trust, which has a long history of supporting a broad cross-section of academic and research initiatives at the University of Iowa.  Funding was matched by the College of Engineering.

The laboratory is a shared resource for the study of how cells, fluids, tissues, organs, and implants respond to physical forces.  Affiliated biomedical engineering faculty include Seth Dillard, lecturer and laboratory manager; Michael Mackey, associate professor; M.L. Raghavan, Robert and Virginia Wheeler Faculty Fellow of Engineering and professor; Ed Sander, assistant professor: and Sarah Vigmostad, assistant professor.

Laboratory research includes:

  • Assaying cells and tissues to quantify mechano-biological activity
  • Testing tiessue mechanics to understand the mechanical behavior of biological tissues and biomaterials
  • Quantitative imaging of cells using inverted phase contrast time-lapse microscopy and custom software for data acquisition and analysis
  • Simulating blood flow using experimental flow loops to study implant performance under the action of pulsable flow conditions in the heart and vessels
  • Preparing and testing stents used to repair arteries
  • Measuring cellular flow using microscopic particle image velocimetry to study how red blood cell hemolysis and cancer cell metastasis take place

For more photos of the visit, go to